Human pulmonary tuberculosis and doxycycline therapy

In this episode, Catherine Ong explains that adjunctive doxycycline with standard anti-TB treatment suppresses pathological MMPs in pulmonary tuberculosis patients.

Extracellular matrix protein laminin β1 and behaviors in mice

In this episode, Ceng Luo and Zhen-Zhen Li explain that extracellular matrix laminin β1 protects against neuropathic pain and related anxiodepression through integrin β1-dependent actin reorganization.

Zonulin-dependent loss of gut mucosal barrier and MIS-C

In this episode, the authors explain that in multisystem inflammatory syndrome in children (MIS-C), increased gastrointestinal mucosal permeability allows SARS-CoV-2 antigens in the GI tract to leak into the bloodstream, triggering cytokine storm and hyperinflammatory responses.

Hemophilia A and immune response

In this episode, Valder Arruda explains that depletion of the cytokine B cell activating factor in hemophilia A may provide a way to prevent or eradicate factor VIII inhibitors.

Efficient maternal to neonatal transfer of antibodies

In this episode, Michal Kovo explains that antenatal BNT162b2 mRNA vaccination induces a robust maternal humoral response that effectively transfers to the fetus, supporting the role of vaccination during pregnancy.