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Author's Take

In this video collection, authors of findings published in The Journal of Clinical Investigation present personally guided tours of their results. The journal accepts video submissions from authors of recently accepted manuscripts. Instructions can be found on the Author's Take Guidelines page.

S100A8/A9 regulates during chronic tuberculosis

In this episode, Shabaana Khader and Rosemary Swanson discuss how the alarmin S100A8/A9 mediates neutrophil accumulation during progression to chronic TB.


Erythrocyte-derived microvesicles induce arterial spasms

In this Episode, Johanne Poisson, Marion Tanguy, Pierre-Emmanuel Rautou, and colleagues discuss that the high prevalence of myocardial infarction without significant coronary stenosis or atherosclerosis in patients with MPN suggests that vascular function.


MICAL1 constrains and protects against disease by oxidizing CaMKII

In this episode, Mark Anderson explains that the stereospecific redox status of CaMKII Methionine 308 regulates CaMKII activation and determines physiological and pathological cardiac responses to stress across species.


Mature myelin maintenance requires Qki to coactivate metabolism

In this episode, Jian Hu and colleagues demonstrate that continuous lipid synthesis is indispensable for mature myelin maintenance and highlight an underappreciated role of lipid metabolism in demyelinating diseases.


Pancreatic triglyceride lipase mediates lipotoxic systemic inflammation

In this episode, Vijay Singh and colleagues reveal that Pancreatic lipase-mediated necrosis of visceral fat worsens outcomes in acute pancreatitis.

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