In this video collection, authors of findings published in The Journal of Clinical Investigation present personally guided tours of their results. The journal accepts video submissions from authors of recently accepted manuscripts. Instructions can be found on the Author's Take Guidelines page.
In this episode, Li Li explains that in-hospital use of angiotensin receptor blockers was associated with a significant reduction in mortality among COVID-19-positive African American patients.
In this episode, the authors explain that local delivery of the complement C3 inhibitor AMY-101 in patients with gingivitis was safe, well tolerated, and led to significant and sustained reduction of clinical indices of gingival inflammation.
In this episode, Marina Kreutz and colleagues discuss how their findings provide evidence of an immunometabolic dysregulation in COVID-19, which can be mitigated by dexamethasone treatment.
In this episode, Jack Elias explains that these studies demonstrate that CHI3L1 contributes to pulmonary metastasis by regulating PD-1-PD-L-1 axis, and simultaneous targeting of CHI3L1 and PD-1/PD-L1 axis elicits synergistic antitumor responses.
In this episode, Peter van der Meer and Mathilde Vermeer explain the pathological role of KLHL24 methionine start-codon mutations in the development of dilated cardiomyopathy using hiPSC-derived dynamically loaded engineered heart tissues.