Elevated tRNA halves in olfactory epithelial cells of patients with schizophrenia

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Justin T. Gumas, Megumi Shigematsu, Karin E. Borgmann-Winter, Chang-Gyu Hahn, Yohei Kirino

Detection of clonal hematopoiesis of indeterminate potential via genome or exome sequencing underestimates disease associations

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Robert Corty, Yash Pershad, J. Brett Heimlich, Caitlyn Vlasschaert, Leo Luo, Taralynn Mack, Kaushik Amancherla, Cassianne Robinson-Cohen, Michael Savona, Alexander G. Bick

Germline inactivation of tumor suppressor BAP1 is associated with white spotting

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Ching-Ni Njauw, Zhenyu Ji, David I. Latoni, Jose Mari Villa-Gonzalez, Shelley McCormick, Raj Kumar, Dmitrii Usoltsev, Mykyta Artomov, Boyi Gan, Hensin Tsao

CAR-T-cells targeting the glycoprotein GD2 show potent anti-tumor efficacy in high-risk ependymoma models

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Antonio Carlos Tallon-Cobos, Konstantinos Vazaios, Piotr Waranecki, Marliek van Hoesel, Annelisa M. Cornel, Benjamin Schwalm, Norman Mack, Ella de Boed, Jasper van der Lugt, Stefan Nierkens, Marcel Kool, Eelco W. Hoving, Dennis S. Metselaar, Esther Hulleman

Functional interrogation of contextually-correct MYH7 variants using CRaTER-flox gene editing and contractility profiling

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Alexander M. Loiben, Wei-Ming Chien, Ashley McKinstry, Dania Ahmed, Matthew C. Childers, Michael Regnier, Charles E. Murry, Kai-Chun Yang

GDF15 is a putative biomarker for distinguishing pulmonary veno-occlusive disease and pulmonary arterial hypertension

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Amit Prabhakar, Eckart M.D.D. De Bie, Jacqueline T. DesJardin, Prajakta Ghatpande, Stefan Gräf, Luke S. Howard, S. John Wort, Colin Church, David G. Kiely, Emily Sumpena, Thin Aung, Shenrae Carter, Jasleen Kukreja, Steven Hays, John R. Greenland, Jonathan P. Singer, Michael Wax, Paul J. Wolters, Marc A. Simon, Mark Toshner, Giorgio Lagna, Akiko Hata

Mechanical strain exacerbates Pseudomonas infection in an organoid-based pneumonia-on-a-chip model

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Karen Hoffmann, Ulrike Behrendt, Peter Pennitz, Holger Kirsten, Jessica Pohl, Elena Lopez-Rodriguez, Chantal Weissfuss, Jens Kollmeier, Mario Tönnies, Sebastian Brill, Konrad Steinestel, Martin Witzenrath, Werner Wenzel, Christian Zobel, Geraldine Nouailles

Neutrophil to lymphocyte ratio varies in magnitude and biomarker utility based on patient demographics

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William Ang, Travis D. Kerr, Ananya Kodiboyena, Cristina Valero, Joris L. Vos, Vladimir Makarov, Alex A. Adjei, Luc G.T. Morris, Stephanie L. Schmit, Natalie L. Silver, Sujata Patil, Daniel J. McGrail

Identification of serum protein biomarkers for clear cell renal cell carcinoma using patient-derived xenografts

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Dalin Zhang, Chun-Lung Chiu, Fernando Jose Garcia Marques, Abel Bermudez, Christian R. Hoerner, Nicholas Hadi, Elise Wang, Thomas J. Metzner, Ludimila Trabanino, John T. Leppert, Hongjuan Zhao, Robert Tibshirani, Alice C. Fan, Sharon J. Pitteri, James D. Brooks

Human adenosine deaminase type 2 deficiency: enhanced NK cell activation but impaired maturation and function

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Jarne Beliën, Amber De Visscher, Bethany Pillay, Marjon Wouters, Verena Kienapfel, Eline Bernaerts, Tania Mitera, Nele Berghmans, Bénédicte Dubois, Leen Moens, Patrick Matthys, Isabelle Meyts