In the quest to provide treatment for COVID-19 patients, available therapies that have been approved for other indications but have insufficient evidence of safety and efficacy for use against COVID-19 have been considered. One of the unintended consequences of this approach is the potential creation of shortages, depriving existing patients who are benefiting from products based on their proven indications. Here, a pharmaceutical company outlines their ethical decision-making framework to guide decision-making and ensure equity of access to products.
Arthur L. Caplan, Joanne Waldstreicher, Karla Childers, Aran Maree
Several important features of Multisystem Inflammatory Syndrome in Children (MIS-C) differentiate it from Kawasaki disease. Rowley et al. discuss what is known about MIS-C and the need to elucidate the specific immune mechanisms underlying hyperinflammatory syndromes caused by SARS-CoV-2 to advance potential targeted treatments and prevention efforts.
Anne H. Rowley, Stanford T. Shulman, Moshe Arditi
Lorraine B. Ware, Kathleen L. Collins, John B. Hawley, Rexford S. Ahima
This Viewpoint describes how physicians and researchers can utilize approaches based on relationship-centered care and structural competence to reduce racism and enhance trustworthiness in health care and biomedical research.
Lisa A. Cooper, Deidra C. Crews
J. Wesley Pike, Mark B. Meyer
Addressing racism from within health care is critically important to creating an equitable society. Here, we provide an actionable framework that can be implemented to build a culture of antiracism in health care systems.
Eugenia C. South, Paris D. Butler, Raina M. Merchant
A retrospective look at how clinical research trials were prioritized in New York City in the wake of the COVID-19 pandemic provides insights for future clinical research efforts.
Roy M. Gulick, Magdalena E. Sobieszczyk, Donald W. Landry, Anthony N. Hollenberg
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) focuses on many diseases that place disparate burdens on minority groups and the poor, such as obesity, diabetes, and kidney disease. Here, we highlight the NIDDK's commitment to combating health disparities through basic, translational, and clinical research.
B. Tibor Roberts, Griffin P. Rodgers
Yasmin L. Hurd
Broadly activating innate immunity, which has been achieved via unrelated vaccines or Type-I INF-like factors, may effectively treat or prevent COVID-19 and future coronavirus diseases.
Leonard Angka, Marisa Market, Michele Ardolino, Rebecca C. Auer
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