Viewpoint
Abstract
In COVID-19, complement activation may contribute to hemostatic activation leading to pathological features such as microvascular injury and coagulopathy.
Authors
Wen-Chao Song, Garret A. FitzGerald
Abstract
Authors
Mark Donowitz, Jerrold R. Turner, Alan S. Verkman, Nicholas Constantine Zachos
Abstract
Authors
Laura E. Crotty Alexander, Amy L. Bellinghausen, Michelle N. Eakin
Abstract
This Viewpoint calls on investigators that are developing and testing therapeutic and prophylactic approaches for COVID-19 to design studies that are inclusive of male-female differences.
Authors
Evelyne Bischof, Jeannette Wolfe, Sabra L. Klein
Abstract
Medications that target catecholamine-associated inflammation may prevent cytokine storm syndrome associated with COVID-19 and other diseases.
Authors
Maximilian F. Konig, Michael A. Powell, Verena Staedtke, Ren-Yuan Bai, David L. Thomas, Nicole M. Fischer, Sakibul Huq, Adham M. Khalafallah, Allison Koenecke, Ruoxuan Xiong, Brett Mensh, Nickolas Papadopoulos, Kenneth W. Kinzler, Bert Vogelstein, Joshua T. Vogelstein, Susan Athey, Shibin Zhou, Chetan Bettegowda
Abstract
Improved pandemic preparedness could be achieved by proactively managing emerging virus threats using available technologies.
Authors
Barney S. Graham, Kizzmekia S. Corbett
Abstract
Authors
Ahmed Khattab, Ian Marshall, Sally Radovick
Abstract
Lessons from the Ebola outbreak shows that it is possible to develop rapid and effective clinical research responses without relying on anecdote.
Authors
Arthur L. Caplan, Ross Upshur
Abstract
Authors
Allen C. Steere
Abstract
The current COVID-19 pandemic has affected everyone, but presents profound consequences for patients with kidney disease, health care providers, and biomedical researchers. In this Viewpoint, I will discuss a number of kidney-specific aspects of COVID-19 infection, noting therapeutic and basic research opportunities.
Authors
Hamid Rabb
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Copyright © 2020 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)