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The TGR5 receptor mediates bile acid-induced itch and analgesia
Carlos Corvera of UCSF and Nigel Bunnett of Monash University discuss their study demonstrating that bile acids cause itch and analgesia by activating the TGR5 receptor in neurons.
Published March 25, 2013
Increased brain uptake and oxidation of acetate in heavy drinkers
Increased brain uptake and oxidation of acetate in heavy drinkers Graeme Mason of Yale University discusses how heavy drinking influences metabolism and leads to alternate fuel use in the brain.
Published March 8, 2013
Brain-wide pathway for waste clearance captured by contrast enhanced MRI
Helene Benveniste of Stony Brook University discusses the use of contrast-enhanced MRI to visualize the glymphatic system, a paravascular pathway that facilitates the clearance of waste and solutes from the cerebrospinal fluid and interstitial fluid of the brain.
Published February 22, 2013
iRHOM2 is a critical pathogenic mediator of inflammatory arthritis
Jane Salmon, Carl Blobel, Priya Darshinee Issuree, and Thorsten Maretzky of the Weill Cornell University Hospital for Special Surgery discuss the role of iRHOM2 in inflammatory arthritis.
Published January 25, 2013
CXCR5+ T helper cells mediate protective immunity against tuberculosis
Shabaana Khader of the University of Pittsburgh discusses the identification of immune parameters that distinguish active and latent TB infections.
Published January 2, 2013
Deimination restores inner retinal visual function in murine demyelinating disease
Sanjoy Bhattarcharya and Vittorio Porciatti of the University of Miami discuss the role of deimination, a post-translational protein modification, in retinal function.
Published January 2, 2013
PSD-95 expression controls
-DOPA dyskinesia through dopamine D1 receptor trafficking
Erwan Bezard and Laurent Groc of the University of Bordeaux discuss the effects of the post-synaptic density protein PSD-95 on the development of levodopa-induced dyskinesia.
Published October 8, 2012
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American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)
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