Fat in the liver and insulin resistance

H Yki‐Järvinen - Annals of medicine, 2005 - Taylor & Francis
Insulin resistance in humans is not always accompanied by obesity, since severe insulin
resistance also characterizes patients lacking subcutaneous fat such as those with HAART‐
(highly‐active antiretroviral therapy)‐associated lipodystrophy. Both obese and
lipodystrophic patients, however, have an increase in the amount of fat hidden in the liver.
Liver fat content can be accurately quantified non‐invasively by proton magnetic resonance
spectroscopy. It is closely correlated with fasting insulin concentrations and direct measures …

The fatty liver and insulin resistance

H Yki-Jarvinen, J Westerbacka - Current molecular medicine, 2005 - ingentaconnect.com
Obesity is not necessary to observe insulin resistance in humans since severe insulin
resistance also characterizes patients lacking subcutaneous fat such as those with HAART
(highlyactive antiretroviral therapy)-associated lipodystrophy. Both the obese and the
lipodystrophic patients have, however, an increase in the amount of fat hidden in the liver.
Liver fat content can be non-invasively accurately quantified by proton magnetic resonance
spectroscopy. It is closely correlated with fasting insulin and direct measures of hepatic …