Murine echocardiography: a practical approach for phenotyping genetically manipulated and surgically modeled mice

F Syed, A Diwan, HS Hahn - Journal of the American Society of …, 2005 - Elsevier
There have now been literally hundreds of genetically manipulated mouse models
developed during the past decade of cardiac research. Echocardiography is considered an
extremely important tool to noninvasively assess and serially follow the phenotype of
genetically and surgically altered mice. This review describes in detail the technical
considerations, various routinely used methods to assess cardiac function, and some
emerging techniques in the assessment of cardiac function in experimental mouse models …