Localization of VIP-immunoreactive nerves in airways and pulmonary vessels of dogs, cats, and human subjects

RD Dey, WA Shannon Jr, SI Said - Cell and tissue research, 1981 - Springer
RD Dey, WA Shannon Jr, SI Said
Cell and tissue research, 1981Springer
VIP-containing neurons were localized in lungs from dogs, cats, and human subjects by
means of the indirect immunofluorescence technique. Nerve fibers and terminals were
observed in the smooth muscle layer and glands of airways, and within the walls of
pulmonary and bronchial vessels, especially at the medial-adventitial junction. VIP-positive
nerve cell bodies were identified in ganglia located in the walls of bronchi. These findings
provide an anatomic basis for the possible modulation of airway and pulmonary vascular …
Summary
VIP-containing neurons were localized in lungs from dogs, cats, and human subjects by means of the indirect immunofluorescence technique. Nerve fibers and terminals were observed in the smooth muscle layer and glands of airways, and within the walls of pulmonary and bronchial vessels, especially at the medial-adventitial junction. VIP-positive nerve cell bodies were identified in ganglia located in the walls of bronchi. These findings provide an anatomic basis for the possible modulation of airway and pulmonary vascular function by this neuropeptide.
Springer