Blood-derived macrophages infiltrate the retina and activate Muller glial cells under experimental choroidal neovascularization
A Caicedo, DG Espinosa-Heidmann, Y Piña… - Experimental eye …, 2005 - Elsevier
Inflammation is a major mechanism in the pathogenesis of age-related macular
degeneration, the most important cause of blindness in the elderly. Previous studies have
focused on the role of macrophages in regulating the growth of pathological new vessels
over the retina, called choroidal neovascularization (CNV). However, no research has been
done to evaluate the role of inflammation as a mechanism of vision loss and retinal
degeneration in the retina underlying CNV. In other neuropathological conditions …
degeneration, the most important cause of blindness in the elderly. Previous studies have
focused on the role of macrophages in regulating the growth of pathological new vessels
over the retina, called choroidal neovascularization (CNV). However, no research has been
done to evaluate the role of inflammation as a mechanism of vision loss and retinal
degeneration in the retina underlying CNV. In other neuropathological conditions …