Interleukin 6 and haemostasis.

R Kerr, D Stirling, CA Ludlam - British journal of …, 2001 - search.ebscohost.com
R Kerr, D Stirling, CA Ludlam
British journal of haematology, 2001search.ebscohost.com
Review Page 1 British Journal of Haematology, 2001, 115, 3ą12 Review INTERLEUKIN 6 AND
HAEMOSTASIS Interleukin 6 (IL-6) is a 26 kDa protein produced by many cell types including
activated monocytes and macrophages, endothelial cells, adipose cells and the Th-2 subset
of Thelper cells (Aarden et al, 1987; Jirik et al, 1989; MohamedAli et al, 1997; Laharrague et
al, 2000). After interaction with a specific saturable receptor, present on a great variety of
responsive cells, it promotes a range of activities (Fig 1 and Table I) including antiviral effects …
Abstract
Presents a literature review on interleukin 6 (IL-6) and haemostasis. Significance of IL-6 in the treatment of haemostasis; Information on IL-6 and its receptors; Coverage of the IL-6 cytokine family.
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