Mechanism of the defect in cholesteryl ester clearance from macrophages of atherosclerosis-susceptible White Carneau pigeons.
PG Yancey, RW St Clair - Journal of lipid research, 1994 - ASBMB
Recent studies from our laboratory (Yancey, PG, and RW St. Clair. 1992. Arterioscler.
Thromb. 12: 1291-1304) have shown that cultured peritoneal macrophages from White
Carneau (WC) pigeons clear cholesteryl esters at a slower rate than do macrophages from
Show Racer (SR) pigeons (9% per 24 h vs. 42% per 24 h, respectively) when incubated in
the presence of a cholesterol acceptor apo high density lipoprotein/phosphatidylcholine
(apoHDL/PC) at concentrations that are not rate-limiting for cholesterol efflux. In the present …
Thromb. 12: 1291-1304) have shown that cultured peritoneal macrophages from White
Carneau (WC) pigeons clear cholesteryl esters at a slower rate than do macrophages from
Show Racer (SR) pigeons (9% per 24 h vs. 42% per 24 h, respectively) when incubated in
the presence of a cholesterol acceptor apo high density lipoprotein/phosphatidylcholine
(apoHDL/PC) at concentrations that are not rate-limiting for cholesterol efflux. In the present …