Stabilisation of neuromuscular junctions by leupeptin increases motor unit size in partially denervated rat muscles
F Tyč, G Vrbova - Developmental brain research, 1995 - Elsevier
The effect of inhibiting the calcium activated neutral protease (CAMP) by leupeptin on force
output and motor unit size of the partially denervated rat EDL muscle was studied. Partial
denervation was performed under anaesthesia by section of the L4 ventral ramus in 3-and
18-day-old Wistar rats. Two days after the operation a silicon strip containing the inhibitor of
CAMP leupeptin was implanted alongside the partially denervated EDL. Two to 3 months
later the animals were anaesthetised and the EDL muscles on both sides prepared for …
output and motor unit size of the partially denervated rat EDL muscle was studied. Partial
denervation was performed under anaesthesia by section of the L4 ventral ramus in 3-and
18-day-old Wistar rats. Two days after the operation a silicon strip containing the inhibitor of
CAMP leupeptin was implanted alongside the partially denervated EDL. Two to 3 months
later the animals were anaesthetised and the EDL muscles on both sides prepared for …