A role of cytokines in OK-432 injection therapy for cystic lymphangioma: an approach to the mechanism
A Fujino, Y Moriya, Y Morikawa, K Hoshino… - Journal of pediatric …, 2003 - Elsevier
Purpose: This study examines cytokine levels of aspirates from cystic lymphangiomas after
injection of OK-432 and over the course of several weeks to better understand the process of
tumor regression. Methods: Fluids aspirated from lymphangioma cysts of 3 patients were
collected sequentially before and after OK-432 injection. Mononuclear cells (MNCs) were
separated and cultured with or without OK-432. Vascular endothelial growth factor (VEGF),
soluble VEGF receptor 1 (sVEGFR1), sVEGFR2, transforming growth factor beta-1 (TGF-β1) …
injection of OK-432 and over the course of several weeks to better understand the process of
tumor regression. Methods: Fluids aspirated from lymphangioma cysts of 3 patients were
collected sequentially before and after OK-432 injection. Mononuclear cells (MNCs) were
separated and cultured with or without OK-432. Vascular endothelial growth factor (VEGF),
soluble VEGF receptor 1 (sVEGFR1), sVEGFR2, transforming growth factor beta-1 (TGF-β1) …