Leptin facilitates learning and memory performance and enhances hippocampal CA1 long-term potentiation and CaMK II phosphorylation in rats
Y Oomura, N Hori, T Shiraishi, K Fukunaga, H Takeda… - Peptides, 2006 - Elsevier
Leptin, an adipocytokine encoded by an obesity gene and expressed in adipose tissue,
affects feeding behavior, thermogenesis, and neuroendocrine status via leptin receptors
distributed in the brain, especially in the hypothalamus. Leptin may also modulate the
synaptic plasticity and behavioral performance related to learning and memory since: leptin
receptors are found in the hippocampus, and both leptin and its receptor share structural
and functional similarities with the interleukin-6 family of cytokines that modulate long-term …
affects feeding behavior, thermogenesis, and neuroendocrine status via leptin receptors
distributed in the brain, especially in the hypothalamus. Leptin may also modulate the
synaptic plasticity and behavioral performance related to learning and memory since: leptin
receptors are found in the hippocampus, and both leptin and its receptor share structural
and functional similarities with the interleukin-6 family of cytokines that modulate long-term …