Risperidone in the treatment of disruptive behavioral symptoms in children with autistic and other pervasive developmental disorders

S Shea, A Turgay, A Carroll, M Schulz, H Orlik… - …, 2004 - publications.aap.org
Objective. To investigate the efficacy and safety of risperidone for the treatment of disruptive
behavioral symptoms in children with autism and other pervasive developmental disorders
(PDD). Methods. In this 8-week, randomized, double-blind, placebo-controlled trial,
risperidone/placebo solution (0.01–0.06 mg/kg/day) was administered to 79 children who
were aged 5 to 12 years and had PDD. Behavioral symptoms were assessed using the
Aberrant Behavior Checklist (ABC), Nisonger Child Behavior Rating Form, and Clinical …