Steroid hormones are derived from cholesterol and can be classified into sex hormones
(estrogens, androgens, progesterone) that are primarily synthesized in the gonads and
adrenal hormones (glucocorticoids and mineralocorticoids) that are primarily synthesized in
the adrenal gland. Although, it has long been known that steroid hormones have potent
effects on the immune system, recent studies have led to renewed interest in their role in
regulating anti-tumor immunity. Extra-glandular cells, such as epithelial cells and immune …