Catecholamines modulate podocyte function.

TB Huber, J Gloy, A Henger… - Journal of the …, 1998 - journals.lww.com
The aim of this study was to investigate the influence of adrenoceptor agonists on the
intracellular calcium activity ([Ca2+] i), membrane voltage (Vm), and ion conductances (Gm)
in differentiated mouse podocytes.[Ca2+] i was measured by the Fura-2 fluorescence
method in single podocytes. Noradrenaline and the alpha 1-adrenoceptor agonist
phenylephrine induced a reversible and concentration-dependent biphasic increase of
[Ca2+] i in podocytes (EC50 approximately 0.1 microM for peak and plateau), whereas the …