Proto-oncogene c-fos and the regulation of vasopressin gene expression during dehydration

JM Ding, WC Carver, L Terracio, J Buggy - Molecular brain research, 1994 - Elsevier
Secretion of the antidiuretic hormone (ADH) vasopressin is increased when body fluid
homeostasis is disturbed by dehydration. Associated with this increased secretion is an
elevation of vasopressin mRNA in magnocellular hypothalamic neurons projecting to the
posterior pituitary. The proto-oncogene c-fos codes for a nuclear phospho-protein Fos which
binds to specific DNA elements and acts as a transcriptional regulator coupling short-term
extracellular stimuli to long-term responses by altering secondary target gene expression …