Importance Complete metastatic ablation of oligometastatic prostate cancer may provide an
alternative to early initiation of androgen deprivation therapy (ADT). Objective To determine
if stereotactic ablative radiotherapy (SABR) improves oncologic outcomes in men with
oligometastatic prostate cancer. Design, Setting, and Participants The Observation vs
Stereotactic Ablative Radiation for Oligometastatic Prostate Cancer (ORIOLE) phase 2
randomized study accrued participants from 3 US radiation treatment facilities affiliated with …