A validated T cell radiomics score is associated with clinical outcomes following multisite SBRT and pembrolizumab
Purpose Combining immune checkpoint blockade (ICB) with stereotactic body radiation
therapy (SBRT) may improve the local response to radiation and the systemic response to
immunotherapy. However, no prognostic markers exist to identify patients likely to benefit
from combined therapy. The degree of T cell–mediated immunity, which can be quantified
with radiomics using computed tomography (CT) imaging, is predictive of immunotherapy
response. Herein we investigated whether a validated T cell radiomics score (RS) is …
therapy (SBRT) may improve the local response to radiation and the systemic response to
immunotherapy. However, no prognostic markers exist to identify patients likely to benefit
from combined therapy. The degree of T cell–mediated immunity, which can be quantified
with radiomics using computed tomography (CT) imaging, is predictive of immunotherapy
response. Herein we investigated whether a validated T cell radiomics score (RS) is …