The SGLT2i dapagliflozin reduces RV mass independent of changes in RV pressure induced by pulmonary artery banding
KA Connelly, E Wu, A Visram, MK Friedberg… - … drugs and therapy, 2022 - Springer
Background Sodium glucose linked transporter 2 (SGLT2) inhibition not only reduces
morbidity and mortality in patients with diagnosed heart failure but also prevents the
development of heart failure hospitalization in those at risk. While studies to date have
focused on the role of SGLT2 inhibition in left ventricular failure, whether this drug class is
efficacious in the treatment and prevention of right heart failure has not been explored.
Hypothesis We hypothesized that SGLT2 inhibition would reduce the structural, functional …
morbidity and mortality in patients with diagnosed heart failure but also prevents the
development of heart failure hospitalization in those at risk. While studies to date have
focused on the role of SGLT2 inhibition in left ventricular failure, whether this drug class is
efficacious in the treatment and prevention of right heart failure has not been explored.
Hypothesis We hypothesized that SGLT2 inhibition would reduce the structural, functional …
The SGLT2i Dapagliflozin Reduces RV Hypertrophy Independent of Changes in RV Pressure Induced by Pulmonary Artery Banding
K Connelly, E Wu, A Visram, MK Friedberg, SN Batchu… - 2021 - researchsquare.com
Background—Sodium glucose linked transporter 2 (SGLT2) inhibition not only reduces
morbidity and mortality in patients with diagnosed heart failure but also prevents the
development of heart failure hospitalization in those at risk. While studies to date have
focused on the role of SGLT2 inhibition in left ventricular failure, whether this drug class
might be similarly efficacious in the treatment and prevention of right heart failure has not
been unexplored. Hypothesis: We hypothesized that SGLT2 inhibition would reduce the …
morbidity and mortality in patients with diagnosed heart failure but also prevents the
development of heart failure hospitalization in those at risk. While studies to date have
focused on the role of SGLT2 inhibition in left ventricular failure, whether this drug class
might be similarly efficacious in the treatment and prevention of right heart failure has not
been unexplored. Hypothesis: We hypothesized that SGLT2 inhibition would reduce the …