Objective:

To investigate associations between shiftwork and glomerular filtration rate among white/Hispanic (n= 273) and African American (n= 81) police officers.

Methods:

Analysis of variance/analysis of variance was utilized to compare mean values of estimated glomerular filtration rate (eGFR) across shiftwork categories.

Results:

Shiftwork was significantly associated with eGFR among white/Hispanic officers only: day (88.6±2.8), afternoon (90.6±2.9), and night shift (83.1±3.1 mL/min/1.73 m 2); afternoon versus night, P= 0.007. Percentage of hours worked on the night shift was inversely associated with mean levels of eGFR, trend P= 0.001. Body mass index modified the association between shiftwork and eGFR (interaction P= 0.038). Among officers with body mass index 25 kg/m 2 or higher, those who worked the night shift had the lowest mean eGFR (afternoon vs night, P= 0.012; day vs night, P= 0.029).

Conclusions:

Night-shift work was associated with decreased kidney function among white/Hispanic officers. Longitudinal studies are warranted among all races.