High mobility group A: a novel biomarker and therapeutic target in pancreatic adenocarcinoma
SS Liau, E Whang - The Surgeon, 2009 - Elsevier
High mobility group A1 (HMGA1) proteins are architectural transcriptional factors that are
over-expressed in a wide range of human malignancies. Recently published evidence
suggests HMGA1 is a promising candidate biomarker and therapeutic target in pancreatic
cancer. This review summarises data implicating HMGA1 as an important mediator of
progression in human cancer and in pancreatic cancer.
over-expressed in a wide range of human malignancies. Recently published evidence
suggests HMGA1 is a promising candidate biomarker and therapeutic target in pancreatic
cancer. This review summarises data implicating HMGA1 as an important mediator of
progression in human cancer and in pancreatic cancer.