Effect of bamlanivimab as monotherapy or in combination with etesevimab on viral load in patients with mild to moderate COVID-19: a randomized clinical trial
Importance Coronavirus disease 2019 (COVID-19) continues to spread rapidly worldwide.
Neutralizing antibodies are a potential treatment for COVID-19. Objective To determine the
effect of bamlanivimab monotherapy and combination therapy with bamlanivimab and
etesevimab on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral load in
mild to moderate COVID-19. Design, Setting, and Participants The BLAZE-1 study is a
randomized phase 2/3 trial at 49 US centers including ambulatory patients (N= 613) who …
Neutralizing antibodies are a potential treatment for COVID-19. Objective To determine the
effect of bamlanivimab monotherapy and combination therapy with bamlanivimab and
etesevimab on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral load in
mild to moderate COVID-19. Design, Setting, and Participants The BLAZE-1 study is a
randomized phase 2/3 trial at 49 US centers including ambulatory patients (N= 613) who …