Repeated Amblyomma testudinarium tick bites are associated with increased galactose-α-1, 3-galactose carbohydrate IgE antibody levels: a retrospective cohort …
H Hashizume, T Fujiyama, T Umayahara… - Journal of the American …, 2018 - Elsevier
Background Alpha-gal syndrome is a hypersensitivity reaction to red meat mediated by IgE
antibody specific to galactose-α-1, 3-galactose carbohydrate (alpha-gal). Amblyomma tick
bites are associated with this condition, but the pathophysiology is not understood. Objective
To clarify the mechanism of development of alpha-gal syndrome after tick bites. Methods We
compared alpha-gal antibody levels between patients with and without a history of tick bites
and examined histologic stainings of tick bite lesions between patients with and without …
antibody specific to galactose-α-1, 3-galactose carbohydrate (alpha-gal). Amblyomma tick
bites are associated with this condition, but the pathophysiology is not understood. Objective
To clarify the mechanism of development of alpha-gal syndrome after tick bites. Methods We
compared alpha-gal antibody levels between patients with and without a history of tick bites
and examined histologic stainings of tick bite lesions between patients with and without …