Location of the Trans-Activating Region on the Genome of Human T-Cell Lymphotropic Virus Type III
J Sodroski, R Patarca, C Rosen, F Wong-Staal… - Science, 1985 - science.org
J Sodroski, R Patarca, C Rosen, F Wong-Staal, W Haseltine
Science, 1985•science.orgThe retrovirus involved in acquired immune deficiency syndrome (HTLV-III/LAV) contains a
region that is necessary for stimulation of gene expression directed by the viral long terminal
repeat. This region is located between nucleotides 5365 and 5607, immediately 5′ to the
envelope gene. A doubly-spliced message containing this region could encode an 86-
amino acid protein with structural features similar to those of nucleic acid-binding proteins.
region that is necessary for stimulation of gene expression directed by the viral long terminal
repeat. This region is located between nucleotides 5365 and 5607, immediately 5′ to the
envelope gene. A doubly-spliced message containing this region could encode an 86-
amino acid protein with structural features similar to those of nucleic acid-binding proteins.
The retrovirus involved in acquired immune deficiency syndrome (HTLV-III/LAV) contains a region that is necessary for stimulation of gene expression directed by the viral long terminal repeat. This region is located between nucleotides 5365 and 5607, immediately 5′ to the envelope gene. A doubly-spliced message containing this region could encode an 86-amino acid protein with structural features similar to those of nucleic acid-binding proteins.
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