[HTML][HTML] Antigen-specific regulatory T-cell responses against aeroantigens and their role in allergy
P Bacher, A Scheffold - Mucosal immunology, 2018 - Elsevier
The mucosal immune system of the respiratory tract is specialized to continuously monitor
the external environment and to protect against invading pathogens, while maintaining
tolerance to innocuous inhaled particles. Allergies result from a loss of tolerance against
harmless antigens characterized by formation of allergen-specific Th2 cells and IgE.
Tolerance is often described as a balance between harmful Th2 cells and various types of
protective “regulatory” T cells. However, the identity of the protective T cells in healthy vs …
the external environment and to protect against invading pathogens, while maintaining
tolerance to innocuous inhaled particles. Allergies result from a loss of tolerance against
harmless antigens characterized by formation of allergen-specific Th2 cells and IgE.
Tolerance is often described as a balance between harmful Th2 cells and various types of
protective “regulatory” T cells. However, the identity of the protective T cells in healthy vs …