High incidence of Epstein–Barr virus, cytomegalovirus, and human-herpes virus-6 reactivations in critically ill patients with COVID-19
A Simonnet, I Engelmann, AS Moreau, B Garcia… - Infectious Diseases …, 2021 - Elsevier
Background Systemic reactivation of herpesviruses may occur in intensive care unit (ICU)
patients and is associated with morbidity and mortality. Data on severe Coronavirus disease-
19 (COVID-19) and concomitant reactivation of herpesviruses are lacking. Methods We
selected patients admitted to ICU for confirmed COVID-19 who underwent systematic testing
for Epstein–Barr virus (EBV), cytomegalovirus (CMV) and human-herpes virus-6 (HHV-6)
DNAemia while in the ICU. We retrospectively analysed frequency, timing, duration and co …
patients and is associated with morbidity and mortality. Data on severe Coronavirus disease-
19 (COVID-19) and concomitant reactivation of herpesviruses are lacking. Methods We
selected patients admitted to ICU for confirmed COVID-19 who underwent systematic testing
for Epstein–Barr virus (EBV), cytomegalovirus (CMV) and human-herpes virus-6 (HHV-6)
DNAemia while in the ICU. We retrospectively analysed frequency, timing, duration and co …