Ara h 2–specific IgE is superior to whole peanut extract–based serology or skin prick test for diagnosis of peanut allergy in infancy

C Keet, M Plesa, D Szelag, W Shreffler, R Wood… - Journal of Allergy and …, 2021 - Elsevier
Background Screening of high-risk infants for peanut allergy (PA) before introduction is now
recommended in the United States, but the optimal approach is not clear. Objective We
sought to compare the diagnostic test characteristics of peanut skin prick test (SPT), peanut-
specific IgE (sIgE), and sIgE to peanut components in a screening population of infants
before known peanut exposure. Methods Infants aged 4 to 11 months with (1) no history of
peanut ingestion, testing, or reaction and (2)(a) moderate-severe eczema,(b) history of food …