[HTML][HTML] Novel importin-α family member Kpna7 is required for normal fertility and fecundity in the mouse
J Hu, F Wang, Y Yuan, X Zhu, Y Wang, Y Zhang… - Journal of Biological …, 2010 - ASBMB
Nuclear importing system and nuclear factors play important roles in mediating nuclear
reprogramming and zygotic gene activation. However, the components and mechanisms
that mediate nuclearly specific targeting of the nuclear proteins during nuclear
reprogramming and zygotic gene activation remain largely unknown. Here, we identified a
novel member of the importin-α family, AW146299 (KPNA7), which is predominantly
expressed in mouse oocytes and zygotes and localizes to the nucleus or spindle. Mutation …
reprogramming and zygotic gene activation. However, the components and mechanisms
that mediate nuclearly specific targeting of the nuclear proteins during nuclear
reprogramming and zygotic gene activation remain largely unknown. Here, we identified a
novel member of the importin-α family, AW146299 (KPNA7), which is predominantly
expressed in mouse oocytes and zygotes and localizes to the nucleus or spindle. Mutation …