Effect of selective serotonin reuptake inhibitors on the risk of fracture

JB Richards, A Papaioannou, JD Adachi… - Archives of internal …, 2007 - jamanetwork.com
Background Depression and osteoporotic fractures are common ailments among elderly
persons. Selective serotonin reuptake inhibitors (SSRIs) are frequently used in the treatment
of depression in this population, and the association between daily SSRI use and fragility
fractures is unclear. Our objective was to examine the effect of daily SSRI use on the risk of
incident clinical fragility fracture. Methods A population-based, randomly selected,
prospective cohort study of 5008 community-dwelling adults 50 years and older, followed up …