Soluble urokinase–type plasminogen activator receptor as a prognostic biomarker in critically ill patients
K Donadello, S Scolletta, FS Taccone, C Covajes… - Journal of critical …, 2014 - Elsevier
Purpose The aim of this study was to assess the role of blood soluble urokinase–type
plasminogen activator receptor (suPAR) levels in the diagnosis and prognostication of
sepsis in critically ill patients. Methods Serum suPAR levels were measured prospectively in
adult intensive care unit (ICU) patients on admission and then daily until ICU discharge
(maximum of 14 days) using an enzyme-linked immunosorbent assay kit. Normal levels
were established in 31 healthy controls. Results We included 258 patients (161 men); …
plasminogen activator receptor (suPAR) levels in the diagnosis and prognostication of
sepsis in critically ill patients. Methods Serum suPAR levels were measured prospectively in
adult intensive care unit (ICU) patients on admission and then daily until ICU discharge
(maximum of 14 days) using an enzyme-linked immunosorbent assay kit. Normal levels
were established in 31 healthy controls. Results We included 258 patients (161 men); …