Importance Conventional methods to diagnose and monitor chronic kidney disease (CKD) in
children, such as creatinine level and cystatin C–derived estimated glomerular filtration rate
(eGFR) and assessment of proteinuria in spot or timed urine samples, are of limited value in
identifying patients at risk of progressive kidney function loss. Serum soluble urokinase
receptor (suPAR) levels strongly predict incident CKD stage 3 in adults. Objective To
determine whether elevated suPAR levels are associated with renal disease progression in …