Tissue-resident macrophages play an important role in maintaining tissue homeostasis and
innate immune defense against invading microbial pathogens. Brain-resident macrophages
can be classified into microglia in the brain parenchyma and non-parenchymal brain
macrophages, also known as central nervous system-associated or border-associated
macrophages, in the brain-circulation interface. Microglia and non-parenchymal brain
macrophages, including meningeal, perivascular, and choroid plexus macrophages, are …