Vaginal progesterone is associated with decreased group B streptococcus colonisation at term: A retrospective cohort study
M Ma'ayeh, KM Rood, HC Walker… - … Journal of Obstetrics …, 2019 - Wiley Online Library
Objective To investigate whether women using intravaginal progesterone suppositories for
preterm birth prevention during pregnancy will have lower rates of group B streptococcus
(GBS) colonisation at term, compared with women receiving intramuscular 17‐alpha‐
hydroxyprogesterone caproate. Design This was a retrospective observational cohort study
of women who were prescribed a progestogen during their pregnancy for preterm birth
prevention, and who delivered at term. Setting A tertiary referral hospital in central Ohio …
preterm birth prevention during pregnancy will have lower rates of group B streptococcus
(GBS) colonisation at term, compared with women receiving intramuscular 17‐alpha‐
hydroxyprogesterone caproate. Design This was a retrospective observational cohort study
of women who were prescribed a progestogen during their pregnancy for preterm birth
prevention, and who delivered at term. Setting A tertiary referral hospital in central Ohio …
[CITATION][C] Vaginal progesterone is associated with decreased group B Streptococcus colonisation
AO Odibo - BJOG: An International Journal of Obstetrics & …, 2019 - Wiley Online Library
Preterm delivery remains the most significant contributor to perinatal mortality and morbidity.
Progestogen supplementation is now standard care for preterm birth prevention in women
with a singleton gestation and a history of prior spontaneous preterm birth in some countries,
such as the USA. There is still controversy regarding the type of progesterone to use. The
options include weekly intramuscular 17-alpha-hydroxyprogesterone caproate (17-OHP-C)
versus daily intravaginal progesterone suppository when access to 17-OHPC is limited …
Progestogen supplementation is now standard care for preterm birth prevention in women
with a singleton gestation and a history of prior spontaneous preterm birth in some countries,
such as the USA. There is still controversy regarding the type of progesterone to use. The
options include weekly intramuscular 17-alpha-hydroxyprogesterone caproate (17-OHP-C)
versus daily intravaginal progesterone suppository when access to 17-OHPC is limited …