The decline in skeletal muscle mass with aging is mainly attributed to a reduction in type II muscle fiber size

R Nilwik, T Snijders, M Leenders, BBL Groen… - Experimental …, 2013 - Elsevier
BACKGROUND: The loss of skeletal muscle mass with aging has been attributed to a
decline in muscle fiber number and muscle fiber size. OBJECTIVE: To define to what extent
differences in leg muscle cross-sectional area (CSA) between young and elderly men are
attributed to differences in muscle fiber size. METHODS: Quadriceps muscle CSA and type I
and type II muscle fiber size were measured in healthy young (n= 25; 23±1y) and older (n=
26; 71±1y) men. Subsequently, the older subjects performed 6months of resistance type …