A multicenter study of the efficacy of the ketogenic diet

EPG Vining, JM Freeman, K Ballaban-Gil… - Archives of …, 1998 - jamanetwork.com
Objective To determine the efficacy of the ketogenic diet in multiple centers. Design A
prospective study of the change in frequency of seizures in 51 children with intractable
seizures who were treated with the ketogenic diet. Setting Patients were enrolled from the
clinical practices of 7 sites. The diet was initiated in-hospital and the patients were followed
up for at least 6 months. Patients Fifty-one children, aged 1 to 8 years, with more than 10
seizures per week, whose electroencephalogram showed generalized epileptiform …