Persistent exertional intolerance after COVID-19: insights from invasive cardiopulmonary exercise testing

I Singh, P Joseph, PM Heerdt, M Cullinan… - Chest, 2022 - Elsevier
Background Some patients with COVID-19 who have recovered from the acute infection
after experiencing only mild symptoms continue to exhibit persistent exertional limitation that
often is unexplained by conventional investigative studies. Research Question What is the
pathophysiologic mechanism of exercise intolerance that underlies the post-COVID-19 long-
haul syndrome in patients without cardiopulmonary disease? Study Design and Methods
This study examined the systemic and pulmonary hemodynamics, ventilation, and gas …