Postmortem assessment of olfactory tissue degeneration and microvasculopathy in patients with COVID-19

CY Ho, M Salimian, J Hegert, J O'Brien, SG Choi… - JAMA …, 2022 - jamanetwork.com
Importance Loss of smell is an early and common presentation of COVID-19 infection.
Although it has been speculated that viral infection of olfactory neurons may be the culprit, it
is unclear whether viral infection causes injuries in the olfactory bulb region. Objective To
characterize the olfactory pathology associated with COVID-19 infection in a postmortem
study. Design, Setting, and Participants This multicenter postmortem cohort study was
conducted from April 7, 2020, to September 11, 2021. Deceased patients with COVID-19 …