[HTML][HTML] Maternal microchimerism in healthy adults in lymphocytes, monocyte/macrophages and NK cells
LS Loubière, NC Lambert, LJ Flinn, TD Erickson… - Laboratory …, 2006 - Elsevier
During pregnancy some maternal cells reach the fetal circulation. Microchimerism (Mc)
refers to low levels of genetically disparate cells or DNA. Maternal Mc has recently been
found in the peripheral blood of healthy adults. We asked whether healthy women have
maternal Mc in T and B lymphocytes, monocyte/macrophages and NK cells and, if so, at
what levels. Cellular subsets were isolated after fluorescence activated cell sorting. A panel
of HLA-specific real-time quantitative PCR assays was employed targeting maternal-specific …
refers to low levels of genetically disparate cells or DNA. Maternal Mc has recently been
found in the peripheral blood of healthy adults. We asked whether healthy women have
maternal Mc in T and B lymphocytes, monocyte/macrophages and NK cells and, if so, at
what levels. Cellular subsets were isolated after fluorescence activated cell sorting. A panel
of HLA-specific real-time quantitative PCR assays was employed targeting maternal-specific …