Characterization of CCR9 expression and thymus-expressed chemokine responsiveness of the murine thymus, spleen and mesenteric lymph node

HS Lee, HR Kim, EH Lee, MH Jang, SB Kim, JW Park… - Immunobiology, 2012 - Elsevier
CC chemokine receptor 9 (CCR9) is a receptor expressed at high levels in immature
thymocytes, small intestine trafficking T cells and IgA-producing plasma cells. CCR9
mediates chemotaxis in response to thymus-expressed chemokine (TECK) selectively
expressed in the thymus and small intestine. CCR9 expression in different subpopulations of
thymus, spleen and mesenteric lymph node (MLN) cells was analyzed by flow cytometry and
TECK responsiveness of those lymphoid cells was assessed by a Transwell migration …