The Ca 2+-activated monovalent cation channel Trpm5 is a key element in
chemotransduction of taste receptor cells of the tongue, but the extent to which Trpm5
channels are expressed in olfactory sensory neurons (OSNs) of the main olfactory
epithelium (MOE) of adult mice as part of a specific pheromonal detection system is debated.
Here, we used a novel Trpm5-IRES-Cre knockin strain to drive Cre recombinase expression,
employed previously validated Trpm5 antibodies, performed in situ hybridization …