Immunohistochemical expression of Hsp60 correlates with tumor progression and hormone resistance in prostate cancer
C Castilla, B Congregado, JM Conde, R Medina… - Urology, 2010 - Elsevier
OBJECTIVES: To investigate the expression of Hsp60 protein in prostate cancer biopsy
samples, and its association with prognostic clinical parameters and hormone resistance
and survival. Molecular chaperones are involved in protein folding, protein degradation, and
protein trafficking among subcellular compartments. METHODS: We selected 107 patients
with localized and locally advanced prostate cancer at our hospital from 1999 through 2004.
We performed an analysis by western blot and immunohistochemistry on paraffin-embedded …
samples, and its association with prognostic clinical parameters and hormone resistance
and survival. Molecular chaperones are involved in protein folding, protein degradation, and
protein trafficking among subcellular compartments. METHODS: We selected 107 patients
with localized and locally advanced prostate cancer at our hospital from 1999 through 2004.
We performed an analysis by western blot and immunohistochemistry on paraffin-embedded …