Effect of convalescent plasma therapy on time to clinical improvement in patients with severe and life-threatening COVID-19: a randomized clinical trial
Importance Convalescent plasma is a potential therapeutic option for patients with
coronavirus disease 2019 (COVID-19), but further data from randomized clinical trials are
needed. Objective To evaluate the efficacy and adverse effects of convalescent plasma
therapy for patients with COVID-19. Design, Setting, and Participants Open-label,
multicenter, randomized clinical trial performed in 7 medical centers in Wuhan, China, from
February 14, 2020, to April 1, 2020, with final follow-up April 28, 2020. The trial included 103 …
coronavirus disease 2019 (COVID-19), but further data from randomized clinical trials are
needed. Objective To evaluate the efficacy and adverse effects of convalescent plasma
therapy for patients with COVID-19. Design, Setting, and Participants Open-label,
multicenter, randomized clinical trial performed in 7 medical centers in Wuhan, China, from
February 14, 2020, to April 1, 2020, with final follow-up April 28, 2020. The trial included 103 …