Association of prior SARS-CoV-2 infection with risk of breakthrough infection following mRNA vaccination in Qatar
Importance The effect of prior SARS-CoV-2 infection on vaccine protection remains poorly
understood. Objective To assess protection from SARS-CoV-2 breakthrough infection after
mRNA vaccination among persons with vs without prior SARS-CoV-2 infection. Design,
Setting, and Participants Matched-cohort studies in Qatar for the BNT162b2 (Pfizer-
BioNTech) and mRNA-1273 (Moderna) vaccines. A total of 1 531 736 individuals vaccinated
with either vaccine between December 21, 2020, and September 19, 2021, were followed …
understood. Objective To assess protection from SARS-CoV-2 breakthrough infection after
mRNA vaccination among persons with vs without prior SARS-CoV-2 infection. Design,
Setting, and Participants Matched-cohort studies in Qatar for the BNT162b2 (Pfizer-
BioNTech) and mRNA-1273 (Moderna) vaccines. A total of 1 531 736 individuals vaccinated
with either vaccine between December 21, 2020, and September 19, 2021, were followed …