[HTML][HTML] Trout myomaker contains 14 minisatellites and two sequence extensions but retains fusogenic function
A Landemaine, A Ramirez-Martinez… - Journal of Biological …, 2019 - ASBMB
The formation of new myofibers in vertebrates occurs by myoblast fusion and requires
fusogenic activity of the muscle-specific membrane protein myomaker. Here, using in silico
(BLAST) genome analyses, we show that the myomaker gene from trout includes 14
minisatellites, indicating that it has an unusual structure compared with those of other animal
species. We found that the trout myomaker gene encodes a 434–amino acid (aa) protein, in
accordance with its apparent molecular mass (∼ 40 kDa) observed by immunoblotting. The …
fusogenic activity of the muscle-specific membrane protein myomaker. Here, using in silico
(BLAST) genome analyses, we show that the myomaker gene from trout includes 14
minisatellites, indicating that it has an unusual structure compared with those of other animal
species. We found that the trout myomaker gene encodes a 434–amino acid (aa) protein, in
accordance with its apparent molecular mass (∼ 40 kDa) observed by immunoblotting. The …