Aerobic training in patients with myotonic dystrophy type 1

MC Ørngreen, DB Olsen… - Annals of Neurology …, 2005 - Wiley Online Library
MC Ørngreen, DB Olsen, J Vissing
Annals of Neurology: Official Journal of the American Neurological …, 2005Wiley Online Library
The effect of 12 weeks of aerobic training on a cycle ergometer was studied in 12 patients
with myotonic dystrophy. Efficacy was evaluated by cycle testing and muscle morphology
before and after training. Patients increased their maximal oxygen uptake by 14%, the
maximal workload by 11%, muscle fiber diameter increased significantly, and creatine
kinase did not increase with training. The study indicates that aerobic training is safe and
can improve fitness effectively in patients with myotonic dystrophy. Ann Neurol 2005; 57: 754 …
Abstract
The effect of 12 weeks of aerobic training on a cycle ergometer was studied in 12 patients with myotonic dystrophy. Efficacy was evaluated by cycle testing and muscle morphology before and after training. Patients increased their maximal oxygen uptake by 14%, the maximal workload by 11%, muscle fiber diameter increased significantly, and creatine kinase did not increase with training. The study indicates that aerobic training is safe and can improve fitness effectively in patients with myotonic dystrophy. Ann Neurol 2005;57:754–757
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