Population-based prevalence of cerebral cavernous malformations in older adults: Mayo Clinic Study of Aging
KD Flemming, J Graff-Radford, J Aakre… - JAMA …, 2017 - jamanetwork.com
Importance The prevalence of cerebral cavernous malformation (CCM) is unknown. Case
ascertainment in most previous studies was based on autopsy data or clinical convenience
samples, often without detailed clinical or radiologic information. Objective To determine the
prevalence of CCM in a population-based sample of older adults. Design, Setting, and
Participants This prospective imaging study included 4721 participants aged 50 to 89 years
who were enrolled between January 1, 2004, and December 15, 2015, in the Mayo Clinic …
ascertainment in most previous studies was based on autopsy data or clinical convenience
samples, often without detailed clinical or radiologic information. Objective To determine the
prevalence of CCM in a population-based sample of older adults. Design, Setting, and
Participants This prospective imaging study included 4721 participants aged 50 to 89 years
who were enrolled between January 1, 2004, and December 15, 2015, in the Mayo Clinic …