High resolution quantitation of microvascular plasma perfusion in non-ischemic and ischemic rat brain by laser-scanning confocal microscopy
DC Morris, Z Zhang, K Davies, J Fenstermacher… - Brain Research …, 1999 - Elsevier
Laser-scanning confocal microscopy (LSCM) was used to measure at high resolution
cerebral plasma volumes (perfusion) using two fluorescent plasma markers in a rat model of
embolic stroke. This application of LSCM to study the microvascular circulation in embolic
stroke was developed as an alternative to autoradiography to measure cerebral perfusion.
An additional benefit of LSCM is that it quantitates with great accuracy the structural
relationships of the microcirculation to cells and the pathological alterations of the ischemic …
cerebral plasma volumes (perfusion) using two fluorescent plasma markers in a rat model of
embolic stroke. This application of LSCM to study the microvascular circulation in embolic
stroke was developed as an alternative to autoradiography to measure cerebral perfusion.
An additional benefit of LSCM is that it quantitates with great accuracy the structural
relationships of the microcirculation to cells and the pathological alterations of the ischemic …